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Long-Term HRT Implications

Meaning

Long-Term HRT Implications refers to the comprehensive spectrum of clinical effects, both beneficial and adverse, that emerge from the sustained administration of Hormone Replacement Therapy (HRT) over a period extending typically beyond five years. These implications necessitate a continuous, individualized risk-benefit assessment by the prescribing clinician, balancing symptom relief and quality of life against potential risks to cardiovascular, bone, and breast health. Understanding these long-term outcomes, which vary significantly based on the type, dose, and route of hormone delivery, is essential for informed patient consent and responsible therapeutic management.