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Long-Term HRT Effects

Meaning

Long-Term HRT Effects refer to the comprehensive physiological, pathological, and clinical outcomes associated with the sustained use of Hormone Replacement Therapy (HRT) over many years, typically five years or more. These effects encompass a broad spectrum of influences on cardiovascular health, bone density, cognitive function, and the risk profiles for certain hormone-sensitive malignancies. Clinical assessment of long-term HRT requires a careful, individualized risk-benefit analysis, integrating the patient’s baseline health status, the specific hormone regimen used, and the duration of treatment. Continuous, high-fidelity biochemical surveillance is essential for navigating these prolonged therapeutic courses.