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Long-Term Cognitive Endurance

Meaning

Long-Term Cognitive Endurance is the robust capacity of the brain to sustain complex mental effort, maintain high-level executive function, and resist the onset of mental fatigue across extended periods of continuous cognitive load, often spanning an entire workday or multi-day intensive period. This measure reflects the physiological health of the underlying neural energy infrastructure, including cerebral blood flow, oxygenation, and mitochondrial density within key attentional and memory networks. High endurance is a hallmark of a resilient brain, indicating efficient metabolic and neurochemical regulation.