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Long-Term Brain Remodeling

Meaning

Long-Term Brain Remodeling refers to the sustained, structural, and functional changes in the brain’s architecture that occur over extended periods, driven by chronic hormonal, nutritional, and experiential inputs. This process encompasses neurogenesis, synaptogenesis, and alterations in dendritic arborization, fundamentally changing the neural circuitry and affecting enduring cognitive capabilities. Unlike acute modulation, remodeling signifies a durable change in the brain’s physical and functional capacity. It is the basis for lasting cognitive reserve.