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Lipopolysaccharide Detoxification

Meaning

This is the critical, intrinsic biological process by which the body actively neutralizes and facilitates the systemic elimination of Lipopolysaccharides (LPS), which are potent pro-inflammatory endotoxins released from the outer membrane of Gram-negative bacteria, predominantly residing in the gut. Effective, continuous detoxification is paramount, as the systemic translocation of LPS, clinically termed metabolic endotoxemia, is a primary driver of chronic low-grade inflammation, significant insulin resistance, and hepatic stress. The liver and the host immune system are the primary, essential organs responsible for this vital clearance mechanism.