The dual metabolic process involving the breakdown of stored triglycerides into free fatty acids and glycerol (lipolysis) occurring concurrently with the building of new muscle protein (muscle synthesis). Achieving an optimized state where these two processes are favorably balanced supports body recomposition goals. This synergy is often influenced by the timing of nutrient delivery and hormonal milieu.
Origin
Lipolysis originates from Greek roots meaning fat-splitting, while muscle synthesis refers to the creation of muscle tissue proteins. The pairing highlights a desired state of simultaneous catabolism of fat stores and anabolism of lean tissue.
Mechanism
Growth Hormone and associated IGF-1 signaling are key modulators, promoting lipolysis while simultaneously supporting muscle protein accretion when adequate substrate is present. Strategic timing of nutrient intake, particularly essential amino acids, ensures that synthesis outpaces breakdown following appropriate physiological stimuli. This coordinated metabolic activity drives favorable shifts in body composition.
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