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Lipid Raft Signaling

Meaning

Lipid Raft Signaling refers to the function of highly organized, cholesterol and sphingolipid-rich microdomains within the cell membrane that serve as dynamic platforms for concentrating specific receptors, enzymes, and scaffolding proteins. These specialized structures act as cellular communication hubs, ensuring the efficient and spatially compartmentalized transduction of external signals, including those from hormones, neurotransmitters, and growth factors, into the cell’s interior. The integrity and precise composition of lipid rafts are critical determinants of cellular responsiveness and overall endocrine function.