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Lipid Profile Derangement

Meaning

Lipid Profile Derangement refers to an abnormal or unhealthy pattern of circulating lipids and lipoproteins in the blood, encompassing elevated levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides. This is often coupled with reduced levels of high-density lipoprotein cholesterol (HDL-C), creating an unfavorable ratio. This metabolic imbalance is a significant clinical risk factor for the development of atherosclerosis, cardiovascular disease, and metabolic syndrome. Hormonal shifts, particularly the decline of estrogen in women or testosterone in men, can profoundly contribute to this derangement. Correcting this profile is a primary therapeutic goal in preventative health and longevity medicine.