Light Wavelength Specificity refers to the principle that different colors, or wavelengths, of visible and non-visible light elicit distinct, targeted physiological responses within the human body. The biological impact of light is not uniform but depends critically on the energy and wavelength, which determines which photopigments and cellular pathways are activated. This specificity is leveraged in phototherapy and chronobiological interventions for health optimization.
Origin
This concept originates from the study of photobiology and biophysics, recognizing that biological molecules absorb light energy most effectively at specific wavelengths. The discovery of melanopsin, a non-visual photopigment, cemented the understanding that light has direct, non-visual pathways affecting human physiology beyond vision. This led to the targeted use of specific light colors for therapeutic effects.
Mechanism
The mechanism relies on photoreceptors, such as rhodopsin in the rods and cones for vision, and melanopsin in the intrinsically photosensitive retinal ganglion cells (ipRGCs) for circadian signaling. Blue light wavelengths optimally stimulate melanopsin, strongly affecting the master clock, while red and near-infrared wavelengths penetrate tissue to affect mitochondrial cytochrome c oxidase, influencing cellular energy production and repair processes.
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