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Ligand-Receptor Interaction

Meaning

The Ligand-Receptor Interaction is the fundamental molecular event where a signaling molecule, known as a ligand (such as a hormone or neurotransmitter), binds specifically to a receptor protein on or within a target cell. This binding event initiates a cascade of intracellular signals that ultimately dictate the cell’s response and function. The specificity and affinity of this interaction are central to all hormonal communication and biological regulation. It represents the lock-and-key mechanism of the endocrine system.