Lifespan refers simply to the total number of years an individual lives, whereas Healthspan denotes the duration of those years lived in good health, characterized by functional independence and freedom from chronic disease. Our clinical focus is maximizing healthspan, ensuring that increased lifespan is not merely an extension of morbidity but a continuation of robust physiological function. These two metrics must be decoupled for successful longevity.
Origin
The distinction between lifespan and healthspan is a modern construct arising from gerontology and longevity science, emphasizing the quality of extended life rather than just the quantity. It reflects a philosophical shift in medicine from treating acute illness to proactively preserving functional capacity across the entire adult life trajectory.
Mechanism
Healthspan is primarily maintained through mitigating the hallmarks of aging at the cellular level, such as genomic instability and mitochondrial dysfunction. Strategies like Targeted Nutritional Interventions and systemic inflammation attenuation directly support Cellular Repair Kinetics. By optimizing endocrine signaling to support anabolism and metabolic health, we slow the rate of functional decline associated with chronological aging.
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