What is the Origin of Life Quality Span Extension?

This concept evolves from gerontology and longevity science, contrasting with traditional lifespan metrics by incorporating subjective and objective measures of well-being, often heavily influenced by endocrine status. The extension is achieved by mitigating the cellular senescence and hormonal decline associated with chronological aging. It is a metric of functional longevity.

What is the Mechanism of Life Quality Span Extension?

The extension mechanism involves comprehensive strategies aimed at preserving mitochondrial function, optimizing sex hormone levels within physiological optima, and minimizing chronic low-grade inflammation (inflammaging). By supporting the regulatory roles of key hormones like DHEA and optimizing insulin sensitivity, cellular resilience is promoted. This concerted effort preserves tissue responsiveness to vital signals.

Life Quality Span Extension ∞ Area

Life Quality Span Extension

Meaning

Life Quality Span Extension refers to the clinical objective of increasing the duration of life lived in a state of high functional capacity and robust hormonal balance, rather than merely extending total lifespan. This focus prioritizes the maintenance of endocrine health, cognitive sharpness, and physical vitality throughout aging. We aim for years lived well, not just years accumulated.