Life-Long Capability is a clinical and physiological objective that defines the sustained capacity for high-level physical and cognitive function, autonomy, and resilience throughout an individual’s entire lifespan. It is the practical outcome of successfully managing healthspan, ensuring the biological systems retain sufficient reserve to meet the demands of daily life and unexpected stressors. This capability represents true longevity with quality.
Origin
The term is an evolution of the concept of “healthspan,” moving the focus from merely delaying disease onset to actively preserving functional reserve. It integrates principles from gerontology, rehabilitation medicine, and performance science, emphasizing the retention of musculoskeletal, cardiovascular, and neuroendocrine integrity over decades.
Mechanism
Preservation of this capability is driven by maintaining high metabolic flexibility, optimizing mitochondrial function, and preventing the age-related decline in anabolic hormonal signaling. Strategies focus on minimizing chronic low-grade inflammation, sustaining muscle protein synthesis, and ensuring the continued integrity of the neuroendocrine axes, which collectively govern the body’s adaptive capacity.
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