A strategic, precision-based clinical framework for directing therapeutic and lifestyle interventions toward the most impactful biological pathways that govern human longevity and healthspan. The concept involves identifying an individual’s unique biological vulnerabilities and strengths to prioritize treatments that yield the maximum possible increase in both life expectancy and quality of life. It is a highly individualized, data-driven approach to anti-aging medicine.
Origin
This term is a fusion of ‘life extension,’ the goal of increasing lifespan, and ‘vectoring,’ a term from physics and engineering that implies directional force and strategic guidance. It reflects the shift in longevity medicine toward a systematic, engineering-like optimization of biological systems. The strategy relies on complex diagnostics to map the individual’s biological trajectory.
Mechanism
Vectoring utilizes advanced diagnostic data, including telomere length, epigenetic clocks, and comprehensive hormonal and metabolic panels, to create a personalized hierarchy of intervention targets. Treatments are then ‘vectored’ or directed to modulate key longevity pathways, such as mTOR, AMPK, and sirtuins, and to correct specific hormonal imbalances that accelerate aging. This focused approach ensures resources are applied where they will generate the greatest biological return.
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