Life Extension Therapeutics encompasses interventions, often involving advanced endocrinology and cellular biology, designed to slow, halt, or partially reverse the fundamental biological processes underlying aging. These approaches frequently target hormonal pathways, cellular senescence, and metabolic efficiency to promote extended healthspan alongside lifespan. It represents a proactive approach to maintaining peak physiological function.
Origin
This phrase combines “Life Extension,” the pursuit of increased longevity, with “Therapeutics,” the branch of medicine concerned with the treatment of disease. Its origin lies in biogerontology, seeking to optimize endocrine and cellular resilience against age-related decline.
Mechanism
Many such therapeutics aim to optimize hormone profiles, such as modulating growth hormone signaling or improving insulin sensitivity, which are known drivers of aging phenotypes. These interventions might involve senolytics or epigenetic modulators designed to restore youthful cellular signaling environments. The goal is to maintain robust tissue function by mitigating age-associated endocrine drift.
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