A specialized and integrated area of clinical practice and scientific research focused on the neurological processes that fundamentally govern the rate of biological aging and the duration of the human healthspan. The primary objective is to maximize the functional lifespan of the central nervous system and preserve cognitive vitality. This field requires the integration of endocrinology, neurobiology, and regenerative medicine principles.
Origin
This is an emerging, forward-looking term that combines the clinical discipline of ‘Neurology’ with the overarching goals of ‘Life Extension’ science. It formalizes the understanding that sustained brain health is the central determinant of overall longevity and the quality of life in advanced age.
Mechanism
The core mechanism involves targeted interventions to mitigate the key neurological hallmarks of aging, including chronic neuroinflammation, mitochondrial energy failure, and the accumulation of toxic protein aggregates. Strategies focus on optimizing the neuroendocrine environment to maintain protective hormone levels, enhancing cellular repair pathways like autophagy, and vigorously supporting neuroplasticity to ensure the brain remains structurally and functionally adaptable for an extended period.
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