A comprehensive, longitudinal approach to health and wellness that customizes therapeutic and lifestyle interventions based on the distinct physiological and hormonal requirements of different stages of human life. This strategy moves beyond symptom management to proactively maintain peak functional capacity and mitigate age-related decline in endocrine function. It emphasizes continuous biological calibration from young adulthood through senescence.
Origin
A conceptual term integrating the biological principle of the human “life cycle” with the engineering and clinical goal of “optimization,” reflecting a proactive, systems-level health management philosophy. It is rooted in the understanding that biological priorities shift across the lifespan.
Mechanism
Life-cycle optimization involves regular biochemical and hormonal assessment to identify age-specific shifts, such as perimenopausal estrogen decline or age-related testosterone reduction. Interventions are then dynamically adjusted to support cellular senescence pathways, maintain telomere integrity, and sustain neuroendocrine resilience. This ensures the hormonal milieu remains conducive to health and longevity at every stage, preventing the entrenchment of age-related dysfunctions.
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