A class of synthetic or naturally derived small protein molecules used therapeutically to modulate neuroendocrine pathways specifically involved in the regulation and enhancement of sexual desire and function in both males and females. These peptides target specific receptors in the central nervous system and peripheral tissues to restore a healthy, robust libido. Their application is a highly targeted approach to sexual health.
Origin
The development of these peptides stems from decades of research into the hypothalamic-pituitary-gonadal axis and the discovery of neuropeptides, such as melanocortins and kisspeptins, that centrally regulate sexual arousal and motivation. This is a targeted evolution of traditional hormone replacement therapy.
Mechanism
These peptides operate by binding to and activating specific G protein-coupled receptors in the brain, often influencing the release or activity of key neurotransmitters like dopamine and serotonin. This neurochemical modulation directly impacts the psychological drive for sexual activity, while some peptides may also improve peripheral vascular function necessary for physical sexual response.
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