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LH FSH Relationship

Meaning

The LH FSH Relationship describes the dynamic, interdependent regulatory balance between Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH), two critical gonadotropins secreted by the anterior pituitary gland. These hormones govern the function of the gonads—the testes in males and the ovaries in females. The relative concentrations and pulsatile release patterns of LH and FSH are crucial indicators of the health and integrity of the hypothalamic-pituitary-gonadal (HPG) axis, signaling either primary gonadal failure or central regulatory dysfunction. Clinical assessment of this relationship is essential for diagnosing fertility issues, pubertal disorders, and menopausal or andropausal status.