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LH and FSH Optimization

Meaning

LH and FSH optimization is a clinical strategy focused on regulating the pulsatile release and systemic concentrations of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH), the two key gonadotropins secreted by the anterior pituitary gland. The primary goal is to ensure these hormones provide the correct, nuanced signal to the gonads—the testes in men and the ovaries in women—to maintain optimal endogenous production of sex steroids, such as testosterone and estrogen. This optimization is crucial for supporting fertility, maintaining bone density, and sustaining libido. Dysregulation of these pituitary signals often precedes or accompanies primary gonadal failure.