Skip to main content

Leptin Resistance Resolution

Meaning

Leptin Resistance Resolution is the physiological and clinical achievement of restoring normal cellular sensitivity to the satiety-regulating hormone leptin, which is primarily secreted by adipose tissue. In a state of resistance, high leptin levels fail to signal satiety and energy sufficiency to the hypothalamus, contributing to persistent hunger and weight gain. Resolution involves interventions that restore the integrity of the leptin signaling pathway, allowing the body to correctly perceive its energy stores.