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Leptin Resistance Correction

Meaning

Leptin Resistance Correction is the clinical process of restoring the central nervous system’s sensitivity to the anorexigenic and metabolic signals of the adipocyte-derived hormone leptin. In states of chronic positive energy balance, elevated leptin levels often fail to elicit the appropriate satiety and energy expenditure responses, leading to persistent hyperphagia and weight gain. Effective correction is a key therapeutic goal for metabolic health, aiming to restore the homeostatic balance between energy intake and expenditure, which is vital for long-term weight management and hormonal equilibrium.