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Lean Tissue Matrix Accrual

Meaning

Lean Tissue Matrix Accrual is the net positive accumulation of non-fat body mass, primarily encompassing skeletal muscle, bone mineral density, and connective tissue, which is a critical composite biomarker of anabolic health and longevity. This process requires a sustained state where the rate of protein synthesis and cellular regeneration significantly exceeds the rate of catabolic breakdown and tissue degradation. Clinically, promoting lean tissue matrix accrual is central to combating sarcopenia, osteopenia, and the age-related decline in basal metabolic rate and physical resilience. This accrual is essential for maintaining functional independence and metabolic health.