What is the Origin of Lean Muscle Mass Synthesis?

Derived from the constructive process of "synthesis" applied to "lean muscle mass," focusing on the contractile proteins rather than fat or water content. It emphasizes tissue accretion.

What is the Mechanism of Lean Muscle Mass Synthesis?

This synthesis is primarily driven by the anabolic actions of insulin-like growth factor 1 (IGF-1) and testosterone, which stimulate mTOR signaling pathways to increase ribosomal efficiency in translating mRNA into structural muscle proteins following appropriate mechanical stimuli.

Lean Muscle Mass Synthesis

Meaning

The anabolic process of building new skeletal muscle protein structures, requiring sufficient substrate availability and potent anabolic signaling to increase functional muscle mass. This is central to maintaining metabolic health and physical capacity in aging populations.