What is the Origin of Lean Mass Anabolism?

This term is fundamental to exercise physiology and metabolism, defining the positive nitrogen balance required for tissue accretion. It represents the constructive aspect of tissue turnover.

What is the Mechanism of Lean Mass Anabolism?

Anabolism is primarily driven by the activation of the mTOR signaling pathway, which is highly sensitive to adequate amino acid availability and potent anabolic stimuli. Key drivers include sufficient circulating Insulin-like Growth Factor 1 (IGF-1) and the appropriate action of androgens on muscle satellite cells.

Lean Mass Anabolism ∞ Area

Lean Mass Anabolism

Meaning

Lean Mass Anabolism describes the net anabolic state where the synthesis rate of skeletal muscle protein significantly surpasses the rate of protein breakdown, leading to an increase in functional muscle tissue. This is the constructive phase of muscle physiology. It is essential for metabolic health.