The documented longitudinal pattern of change in non-fat body composition, primarily skeletal muscle and bone mineral content, over time within an individual. Tracking this trajectory is essential in hormonal wellness, as anabolic hormones critically influence muscle accretion and maintenance across the lifespan. A favorable trajectory indicates effective metabolic and endocrine support.
Origin
This phrase combines ‘lean body mass,’ a measurable component of body composition, with ‘trajectory,’ implying a path or course through time. It is a term derived from sports science and clinical gerontology, reflecting the need to quantify changes beyond simple body weight. Monitoring the trajectory helps assess the efficacy of interventions aimed at anabolism.
Mechanism
The trajectory is fundamentally governed by the balance between protein synthesis and degradation, heavily influenced by insulin, growth hormone, and androgens. Positive changes occur when anabolic signaling outweighs catabolic signaling, often supported by adequate nutrient intake and resistance exercise stimulus. Negative trajectories often signal systemic endocrine insufficiency or chronic inflammatory states impacting muscle homeostasis.
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