This describes the quantifiable relationship between the mass of metabolically active tissue, predominantly skeletal muscle and organs, and various physiological outcomes such as resting metabolic rate or insulin sensitivity. A positive correlation indicates that greater muscle mass generally supports better endocrine function and higher overall energy expenditure capacity at rest. It is a crucial measure of physiological quality that transcends simple body weight metrics.
Origin
Originating in body composition science, ‘lean body mass’ (LBM) distinguishes active tissue from inert adipose tissue, while ‘correlation’ establishes the statistical link to functional endpoints like strength or metabolism. This relationship is fundamental in understanding how physical activity prescriptions impact overall healthspan trajectories. We examine the metabolic implications inherent in muscle tissue quantity.
Mechanism
The primary mechanism involves skeletal muscle acting as a major site for glucose disposal, serving as a significant sink for circulating insulin during periods of uptake. Therefore, increased LBM inherently enhances whole-body insulin sensitivity by providing more peripheral tissue for glucose utilization, independent of total body fat percentage. Furthermore, muscle tissue contributes substantially to basal energy expenditure, directly influencing the metabolic rate measurement.
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