What is the Origin of Late Menopause?

The concept is an epidemiological and clinical classification within reproductive endocrinology, defined relative to the statistical mean age of menopause, which is approximately 51 years in Western populations. Recognition of its distinct health implications stems from large cohort studies correlating reproductive lifespan with various long-term health outcomes.

What is the Mechanism of Late Menopause?

The physiological basis for late menopause involves a slower rate of primordial follicle depletion from the ovarian reserve, which is likely influenced by genetic factors and potentially by specific environmental or lifestyle variables. Prolonged estrogen exposure is associated with a lower risk of osteoporosis and cardiovascular disease but may also be linked to a marginally increased, albeit complex, risk profile for certain hormone-sensitive cancers.

Late Menopause ∞ Area

Late Menopause

Meaning

The natural cessation of menstruation occurring at an age significantly later than the average age of menopause, typically defined as occurring after 55 years of age. This extended period of ovarian function is associated with prolonged exposure to endogenous estrogen and progesterone, which carries both specific health advantages and potential risks. It is a clinically relevant demarcation in women’s reproductive longevity.