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Laryngeal Remodeling

Meaning

Laryngeal Remodeling refers to the structural and morphological changes that occur in the larynx, specifically the vocal folds and laryngeal cartilages, driven by the sustained influence of sex steroid hormones. This process results in a permanent alteration of the vocal apparatus, typically leading to a significant and irreversible change in voice pitch and quality. It is a prominent and expected secondary sex characteristic in pubertal males and a key clinical consideration in gender-affirming hormone therapy for transgender individuals. This structural modification directly impacts vocal fundamental frequency.