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Ketone Body Utilization

Meaning

Ketone Body Utilization is the metabolic process by which the body shifts from relying primarily on glucose for cellular energy to effectively using ketone bodies—acetoacetate, beta-hydroxybutyrate, and acetone—as an alternative, highly efficient fuel source. This metabolic flexibility is particularly significant for the brain and muscle tissue and is typically induced by states of fasting or a very low-carbohydrate ketogenic diet. It signifies a state of metabolic adaptation.