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Ketogenic Brain Fueling

Meaning

Ketogenic Brain Fueling refers to the metabolic state where the central nervous system predominantly utilizes ketone bodies—specifically beta-hydroxybutyrate (BHB) and acetoacetate—as its primary energy substrate instead of glucose. This physiological shift occurs during periods of carbohydrate restriction or fasting, offering a highly efficient, alternative fuel source for neurons and glia. Optimizing this fueling state is clinically explored for its neuroprotective and cognitive-enhancing benefits.