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Isomeric Impurities

Meaning

Chemical compounds present in a pharmaceutical substance that possess the same molecular formula as the active drug but differ in the spatial arrangement of their atoms. These impurities can be stereoisomers, geometric isomers, or positional isomers, which may have distinct pharmacological properties from the intended therapeutic agent. Their presence is a critical concern in pharmaceutical quality control due to potential differences in efficacy, metabolism, and toxicity.