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Isoflavone Signaling

Meaning

Isoflavone Signaling refers to the biological communication pathways activated by isoflavones, which are a class of naturally occurring plant compounds, specifically phytoestrogens, found abundantly in legumes like soy. These molecules possess a chemical structure similar to endogenous human estrogens and can interact with estrogen receptors (ER-alpha and ER-beta) throughout the body, acting as selective estrogen receptor modulators (SERMs). This signaling can exert tissue-specific hormonal effects, such as mitigating menopausal symptoms or influencing bone density, depending on the receptor type and local concentration. Understanding this signaling is critical for dietary and supplemental strategies in hormonal balance.