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Islet Cell Survival Agents

Meaning

Islet cell survival agents are a class of therapeutic or endogenous molecules that specifically promote the viability, proliferation, and functional integrity of the pancreatic islet beta-cells, which are responsible for insulin production. Preserving these cells is paramount, as their progressive loss or dysfunction is the fundamental defect leading to both type 1 and type 2 diabetes. These agents are crucial for maintaining long-term glucose homeostasis.