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Iron Deficiency Hypothyroidism

Meaning

Iron Deficiency Hypothyroidism describes a specific form of acquired thyroid dysfunction where a significant lack of bioavailable iron impairs the essential synthesis of the thyroid hormones, specifically both thyroxine (T4) and triiodothyronine (T3). Iron functions as a critical cofactor for the enzyme thyroid peroxidase, or TPO, which is absolutely necessary for the iodination and coupling steps in the hormone production pathway. This condition clearly illustrates the intimate and non-negotiable connection between systemic micronutrient status and robust endocrine function.