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Iron Deficiency and Thyroid

Meaning

Iron Deficiency and Thyroid describes the clinically important, bidirectional relationship where inadequate iron stores impair the synthesis and subsequent metabolism of thyroid hormones, potentially causing or significantly worsening a state of hypothyroidism. Iron is an indispensable micronutrient that serves as a vital cofactor for the enzyme thyroid peroxidase (TPO), which is essential for the final steps of T4 and T3 synthesis. A comprehensive clinical approach to thyroid dysfunction must therefore include a thorough assessment and correction of iron status.