Skip to main content

ipRGC Photoreception

Meaning

ipRGC Photoreception refers to the specific process by which intrinsically photosensitive Retinal Ganglion Cells (ipRGCs) within the retina detect and respond to light stimuli, primarily in the blue-green visible spectrum, using the photopigment melanopsin. Unlike the rods and cones responsible for image formation, ipRGCs function as non-visual photoreceptors, providing the critical light signal necessary for regulating the body’s circadian rhythm and pupil reflex. This is the essential biological input for synchronizing the internal clock.