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Inward Rectifier Potassium Current

Meaning

The Inward Rectifier Potassium Current, denoted as IK1 or IK1, is a specific electrical current in cell membranes, primarily found in cardiac myocytes and neurons, which is carried by potassium ions flowing preferentially into the cell at hyperpolarized membrane potentials. This current is crucial for maintaining the stable resting membrane potential of excitable cells, which is typically close to the equilibrium potential for potassium. Its function is essential for stabilizing the cell’s electrical state between action potentials, preventing spontaneous depolarization and ensuring proper rhythmicity in the heart. The term “rectifier” refers to its characteristic of passing current more easily in one direction, specifically inward, hence the name.