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Intraprostatic Metabolism

Meaning

Intraprostatic metabolism describes the complex biochemical processes, including synthesis, degradation, and energy production, that occur specifically within the prostate gland’s cellular environment. This localized metabolic activity is profoundly influenced by androgens, particularly dihydrotestosterone (DHT), which drives prostate growth and function. Dysregulation of this metabolism, such as altered lipid or glucose utilization, is increasingly recognized as a critical factor in the pathogenesis of benign prostatic hyperplasia (BPH) and prostate carcinoma. Understanding these specific metabolic shifts provides targets for novel therapeutic interventions.