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Intramuscular Kinetics

Meaning

Intramuscular Kinetics describes the study of the absorption, distribution, metabolism, and excretion (ADME) of a substance, typically a drug or hormone, following injection directly into the muscle tissue. This administration route is characterized by a relatively slow, sustained release profile, as the substance must diffuse from the muscle depot into the systemic circulation. Understanding these kinetics is crucial for predicting the therapeutic window and determining the appropriate dosing interval for long-acting hormonal preparations. The rate of absorption is significantly influenced by the blood flow and esterification of the compound.