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Intervention Threshold Biomarkers

Meaning

Intervention Threshold Biomarkers are specific, quantifiable physiological or molecular indicators that, when their measured value crosses a predetermined, clinically derived limit, signal the necessity for therapeutic action or lifestyle modification. These markers move beyond standard reference ranges, which often represent population averages, to define personalized, optimal ranges tied directly to an individual’s healthspan and longevity goals. Establishing these thresholds allows for proactive, preemptive clinical intervention before subclinical dysfunction progresses to overt disease pathology or significant hormonal imbalance.