What is the Origin of Internal Velocity?

This term is a conceptualization used in advanced longevity and functional medicine to describe the aggregate pace of essential biological reactions. It draws from the kinetic principles of biochemistry, where reaction rates are critical, and applies them to the entire physiological system. The concept helps clinicians articulate the difference between chronological age and biological function.

What is the Mechanism of Internal Velocity?

The mechanism is fundamentally dependent on optimal mitochondrial function, which provides the necessary ATP energy for all cellular reactions, and the integrity of hormonal receptor signaling. Factors that enhance Internal Velocity include efficient thyroid hormone action, high levels of key metabolic cofactors, and a low cellular burden of oxidative stress. Clinical strategies to improve this metric focus on supporting mitochondrial biogenesis and restoring cellular sensitivity to anabolic and metabolic hormones.

Internal Velocity ∞ Area

Internal Velocity

Meaning

Internal Velocity is a clinical metric and conceptual measure of the efficiency and speed at which the body’s core physiological processes are executed, encompassing metabolic turnover, hormonal signaling cascade response time, and cellular detoxification rates. High Internal Velocity is characteristic of a youthful, metabolically flexible organism capable of rapid adaptation and repair, whereas a decrease signifies age-related slowing of essential biological functions. It is a composite indicator of systemic efficiency.