What is the Origin of Internal Biological Feedback?

The concept is fundamental to cybernetics and physiology, dating back to the recognition of feedback loops in biological systems, most notably Claude Bernard's work on the milieu intérieur. Negative feedback is the dominant form in endocrinology.

What is the Mechanism of Internal Biological Feedback?

The most common mechanism is negative feedback, where a high concentration of a target gland hormone, like cortisol, signals the pituitary and hypothalamus to decrease the release of their respective stimulating hormones. Conversely, low levels trigger increased release. This constant monitoring and adjustment ensures that hormone levels are tightly controlled within a narrow, functional range.

Internal Biological Feedback ∞ Area

Internal Biological Feedback

Meaning

Internal Biological Feedback refers to the self-regulatory mechanisms within the body where the output of a system feeds back to influence its own input, thereby maintaining homeostasis. In the endocrine system, this is primarily seen in the hypothalamic-pituitary-target gland axes, where hormone levels regulate the release of upstream signaling hormones. This continuous, internal communication is essential for physiological stability and adaptation to stress.