Skip to main content

Interleukin-6 Modulation

Meaning

Interleukin-6 Modulation refers to the therapeutic strategy of adjusting the biological activity or circulating concentration of the cytokine Interleukin-6 (IL-6) to influence systemic inflammation and immune function. IL-6 is a pleiotropic cytokine with complex pro-inflammatory and anti-inflammatory roles, acting as a critical mediator between the immune system and the endocrine axis. Clinical modulation is employed to mitigate chronic low-grade inflammation, often termed inflammaging, a key driver of age-related diseases and metabolic dysfunction. This targeted intervention seeks to restore a healthier, more balanced immune-endocrine set point.