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Interleukin-6 Anti-Inflammatory

Meaning

Interleukin-6 Anti-Inflammatory describes the beneficial, protective role of the cytokine Interleukin-6 (IL-6) when it is transiently released from contracting skeletal muscle during exercise. While chronically elevated IL-6 is a hallmark of systemic inflammation, its acute, exercise-induced pulse acts as a myokine to promote systemic anti-inflammatory effects and metabolic regulation. It is a critical example of how context dictates a molecule’s function, differentiating acute beneficial signaling from chronic pathological signaling.