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Interconnected Feedback Loops

Meaning

Interconnected Feedback Loops describe the complex, reciprocal regulatory circuits that exist both within the endocrine system and between the endocrine, nervous, and immune systems, where the output of one gland or pathway influences the activity of others. These loops are the fundamental mechanism for maintaining hormonal homeostasis, ensuring that hormone concentrations are tightly controlled and responsive to both internal and external stimuli. A disruption in one loop can cascade, causing widespread systemic imbalance across multiple axes.