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Inter-System Feedback Loops

Meaning

Inter-System Feedback Loops are the complex, bidirectional communication pathways that exist between different major physiological systems—such as the endocrine, nervous, immune, and metabolic systems—which allow for continuous self-regulation and adaptation to internal and external stressors. These loops involve the constant exchange of chemical messengers like hormones, neurotransmitters, and cytokines, ensuring the maintenance of dynamic equilibrium, or allostasis, across the entire organism. Dysregulation in these intricate loops is often the root cause of many chronic, multifactorial health conditions and is a key target for functional intervention.