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Inter-Individual Variability

Meaning

Inter-Individual Variability refers to the fundamental, measurable differences observed in physiological, biochemical, and pharmacological responses among distinct human subjects, even when exposed to identical stimuli or treatments. This concept is a cornerstone of personalized medicine, acknowledging that factors like genetics, epigenetics, age, sex, and environment cause unique responses to diet, exercise, and hormonal interventions. Recognizing this inherent variability is crucial for moving beyond population-based norms to create truly individualized care plans. It explains why a standardized dose or protocol works well for one person but not for another.