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Integrin Signaling

Meaning

Integrin Signaling describes the crucial bidirectional communication pathways initiated by integrins, which are specialized transmembrane receptors that physically link the cell’s internal cytoskeleton to the extracellular matrix (ECM) or to other adjacent cells. This essential signaling cascade allows the cell to effectively sense its physical environment and transmit complex mechanical and chemical cues across the cell membrane. It is absolutely fundamental for biological processes like cell adhesion, directed migration, controlled proliferation, and differentiation, particularly in the context of tissue repair and embryonic development.