Skip to main content

Insulin Signaling Sensitivity

Meaning

Insulin signaling sensitivity refers to the responsiveness of target cells, particularly in muscle, fat, and liver tissue, to the hormone insulin, which dictates the efficiency of glucose uptake and utilization. Optimal sensitivity means a minimal amount of insulin is required to maintain healthy blood glucose levels, supporting robust metabolic health and energy balance. Impaired sensitivity, or insulin resistance, is a core feature of metabolic dysfunction and has profound downstream effects on hormonal balance, including sex steroid production.